Kees van der Ark

Kees van der Ark


Kees van der Ark

  • Post-doctoral Fellow

Kees van der Ark, MSc, is a microbiologist who undertook his PhD research at the Laboratory of Microbiology at Wageningen University and Research. His research included the development and application of the next generation of probiotic Akkermansia muciniphila.

Van der Ark joined AIGHD in 2017 as a Postdoctoral Researcher in the PIGSs project (Program for Innovative Global prevention of Streptococcus suis). His research aims at unraveling the interaction between the bacterium Streptococcus suis and humans to prevent or cure infections. His tasks also involve reporting on the human epidemiology of this emerging zoonotic pathogen and supervising MSc and PhD students. His research is based at the department of Medical Microbiology at the Academic Medical Center in Amsterdam.


A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice.
Plovier H, Everard A, Druart C, Depommier C, Van Hul M, Geurts L, Chilloux J, Ottman N, Duparc T, Lichtenstein L, Myridakis A, Delzenne NM, Klievink J, Bhattacharjee A, van der Ark KC, Aalvink S, Martinez LO, Dumas ME, Maiter D, Loumaye A, Hermans MP, Thissen JP, Belzer C, de Vos WM, Cani PD.
Nat Med. 2017 Jan;23(1):107-113. doi: 10.1038/nm.4236. Epub 2016 Nov 28.

More than just a gut feeling: constraint-based genome-scale metabolic models for predicting functions of human intestinal microbes.
Kees C. H. van der Ark, Ruben G. A. van Heck, Vitor A. P. Martins Dos Santos, Clara Belzer, and Willem M. de Vos. Microbiome. 2017; 5: 78.
Published online 2017 Jul 14. doi: 10.1186/s40168-017-0299-x

Adaptation of Akkermansia muciniphila to the oxic-anoxic interface of the mucus layer.
Ouwerkerk JP, van der Ark KC, Davids M, Claassens NJ, Robert Finestra T, de Vos WM, Belzer C.
Appl Environ Microbiol. 2016 Sep 23. pii: AEM.01641-16

Encapsulation of the therapeutic microbe Akkermansia muciniphila in a double emulsion enhances survival in simulated gastric conditions.
Author links open overlay panel Kees C.H. van der Ark, Avis Dwi Wahyu Nugroho, Claire Berton-Carabin, Che Wang, Clara Belzer, Willem M. de Vos, Karin Schroen.
Food Res Int, 2017