Trial of Excellence in Southern Africa III


  1. To promote and consolidate the TESA network activities across the region and expand the network by onboarding countries that are not yet part of the network;
  2. To use the established regional reference laboratories and joint clinical trials for on-the-job training in malaria, HIV/AIDS, and tuberculosis, provide financial support for infrastructure upgrades and promote basic studies for the LDS to allow hands-on training;
  3. To establish and promote capacity built from TESA, including data management, data analysis and data sharing across the network;
  4. To establish a joint platform with national and regional agencies to develop and strengthen collaboration for research evidence sharing that will contribute to the decision-making process, dialogue between researchers, communities, and policymakers in order to maximize the impact of clinical research in Africa.


Southern Africa is still facing challenges with many infectious diseases, including malaria, HIV/AIDS and tuberculosis. Besides this, many Southern African countries lack well-established research platforms, which could contribute to address some of the key health-related knowledge gaps and inform health policy. Within this specific context, the TESA III consortium aims to develop, strenghten and expand clinical research capacities in Southern Africa for conducting clinical trials with the highest research standards on those infectious diseases responsible for the highest morbidity and mortality in the region.

With TESA III, 15 institutions from 9 African and 3 European countries come together to strengthen and enhance the capacities for clinical research in Southern Africa built during TESA, and to strengthen the collaboration of North-South and South-South networking activities among its members.

To achieve this, TESA III focuses on transfering technology, strengthening the capacities among partner sites in Southern Africa, promoting professional development and scientific leadership and fostering collaborations to maximize impact. TESA develops specific activities aiming to increase researchers critical mass devoted to health, develop first-class institutions engaging clinical trials to prevent poverty-related diseases and promote dialogue between researchers, communities and policymakers.

AIGHD Research Lead

Prof. dr. Frank Cobelens


Botswana-Harvard AIDS Institute Partnership (BHP)

Biomedical Research and Trianing Institute (BRTI)

The University of Cape Town Lung Institute (Pty)

Blantyre Health Research and Training Trust

Instituto Nacional de Investicação em Saúde (INIS)

University of Namibia

European Clinical Research Infrastructure Network (ECRIN-ERIC)

University of Zimbabwe

LT Clinical Research

Baylor College of Medicine Children’s Foundation

Fundación Privada Instituto de Salud Global Barcelona (ISGlobal)

University Teaching Hospital (UTH)

Stellenbosch University

Contact info

Valeria Cristofoli (v.cristofoli@aighd.org)


European & Developing Countries Clinical Trials Partnership (EDCTP)











South Africa