Trials of Excellence for Southern Africa


  1. To strengthen collaboration and optimize the use of resources and infrastructures within the network.
  2. To offer training and mentorship aimed at promoting professional development and scientific leadership in clinical trials.
  3. To strengthen South-South and North-South collaborations between researchers and institutions with a specific focus on supporting less established institutions in building capacity for conducting high quality clinical research.
  4. To encourage and promote networking and dialogue between researchers, communities and policy makers to maximise the impact of clinical research in Africa.


Africa is the continent that concentrates the majority of low resource countries in the world. Beyond the limitations of fragile health systems, most African countries lack well established research platforms, which could contribute to address some of the key health related knowledge gaps and inform health policy. In addition, these countries are the ones enduring the highest burden of disease by infectious diseases (malaria, HIV, tuberculosis).

In particular, Southern Africa is the most affected region in the world in terms of TB incidence rate and HIV prevalence, and although malaria incidence rates are decreasing, the global burden of malaria in most countries in Southern Africa is considerable. Within this specific context, TESA is a network of excellence that aims to develop, strengthen and expand clinical research capacities in the Southern Region of Africa for conducting clinical trials with the highest research standards on those infectious diseases responsible for the highest morbidity and mortality in the region.

With TESA, 16 institutions from 9 African and 4 European countries come together to strengthen and enhance the capacities for clinical research in Southern Africa and increase the collaboration and networking activities among its members.

To achieve this, TESA focuses on strengthening the capacities among partner sites in Southern Africa, promoting professional development and scientific leadership and fostering collaborations to maximize impact. TESA develops specific activities aiming to increase researchers critical mass devoted to health, develop first class institutions engaging clinical trials to prevent poverty-related diseases and promote dialogue between researches, communities and policy makers.

AIGHD Research Lead

Prof. dr. Frank Cobelens


Fundação Manhiça – Centro de Investigação em Saúde de Manhiça (CISM)
Botswana-Harvard AIDS Institute Partnership (BHP

Stellenbosch University (SUN)

Blantyre Health Research and Training Trust (BHRTT)
University of Zimbabwe College of Health Sciences (UZCHS)
Biomedical Research and Training Institute (BRTI)
Health Research Centre of Angola (CISA)
University of Namibia (UNAM)
University of Cape Town Lung Institute
University Teaching Hospital/School of Medicine and Tropical Diseases Research Centre, (UTHZ)
LT Clinical Research (LTCR)

European Clinical Research Infrastructure Network (ECRIN-ERIC)
ISGlobal – Barcelona Institute for Global Health
Stichting Amsterdam Institute for Global Health and Development (AIGHD)
University College London (UCL)
Uganda National Health Research Organisation (UNHRO)

Contact info

Natacha Berbers (n.berbers@aighd.org)


European & Developing Countries Clinical Trials Partnership (EDCTP)


Africa: Mozambique, South Africa, Botswana, Zambia, Malawi, Zimbabwe, Angola, Namibia, Uganda

Europe: Netherlands, UK, Spain, France