Prevention, Suppression, and Resistance: Antiretroviral Treatment for Children with HIV in Sub-Saharan Africa

Authored by: Ragna Boerma
Thesis Universiteit van Amsterdam
Promotor(s): T.F. Rinke de Wit
Copromotor(s): M. Boele van Hensbroek
Date of thesis defense: 24/03/2017

This thesis describes the virological and clinical outcomes of children with HIV in sub-Saharan Africa who start antiretroviral treatment (ART). We show that pretreatment HIV drug resistance among children is a serious problem in sub-Saharan Africa and that its prevalence is increasing. Children who start first-line ART have much lower virological suppression rates compared to adults and data on long-term treatment outcomes of these children are largely missing. Read more