The burden of schistosomiasis morbidity in African children: validating novel, low-cost and scalable detection tools and optimizing praziquantel treatment

Authored by: Amaya Lopez Bustinduy
Thesis Universiteit van Amsterdam
Promotor(s): M. Boele van Hensbroek
Copromotor(s): C.H. King, J.R. Storthard
Date of thesis defense: 12/06/2015

Schistosomiasis is a parasitic disease that affects over 100 million children in the world living mostly in sub-Saharan Africa. This thesis explored several aspects of the disease affecting the health of children from two African endemic countries: Kenya and Uganda. Epidemiological work revealed a worrisome association between schistosomiasis and malnutrition (both acute and chronic) as well as anaemia. A novel paediatric quality of life assessment was performed in childrenĀ with the disease with a significant decrease in their psychosocial functioning. Read more