11 Apr In the absence of evidence…
Many issues in the management of patients with drug-resistant tuberculosis rely on expert opinions rather than on evidence. Examples are the evaluation of the duration of infectiveness of the patients, the choice of preventive chemotherapy for contacts of patients with drug-resistant tuberculosis, the optimal duration of therapy in individual patients and the best combination of anti-tuberculosis drugs given the drug-resistance pattern of Mycobacterium tuberculosis.
This manuscript describes the prevailing expert opinion on 15 of these pressing issues. It has been developed predominantly by physicians treating patients with drug-resistant tuberculosis to reach consensus about difficult management issues relating to the care of these patients, in conjunction with leading researchers.
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