Publications

“Data are surprisingly scanty” Recently published systematic review highlights antimicrobial resistance (AMR) knowledge gap in Low- and Middle-income Countries

Charlie Chaluma Luchen (he/him; AIGHD PhD Fellow and CIDRZ Researcher) recently published a systematic review of the effects of antibiotic children-under-five residing in Low- and Middle-income countries (LMICs). Link to Charlie’s article on PLOS Medicine. The serendipitous discovery of penicillin, the world’s first antibiotic, and the...

25 July, 2023

Starting antiretroviral treatment earlier doesn’t negatively impact adherence and disclosure

People who start antiretroviral treatment early, regardless of their CD4 count, are just as likely to stick to their treatment plan as those who begin their treatment when their CD4 count is low. The mixed methods paper led by the Amsterdam Institute for Global Health and...

07 March, 2019

NEW PUBLICATION: IP-10 Kinetics in the First Week of Therapy are Strongly Associated with Bacteriological Confirmation of Tuberculosis Diagnosis in HIV-Infected Patients

Simple effective tools to monitor the long treatment of tuberculosis (TB) are lacking. Easily measured host derived biomarkers have been identified but need to be validated in larger studies and different population groups. Here we investigate the early response in IP-10 levels (between day 0...

03 November, 2017

The impact of the roll-out of rapid molecular diagnostic testing for tuberculosis on empirical treatment in Cape Town, South Africa

The GeneXpert is a molecular test for tuberculosis (TB) which is much more sensitive than the mainstay of diagnosis in most parts of the world, sputum smear microscopy. South Africa was one of the first countries to implement it as the first-line diagnostic for TB....

07 September, 2017

Text messaging to decrease tuberculosis treatment attrition in TB-HIV co-infection in Uganda

In this non-randomized study in Kampala, Uganda, we implemented an SMS reminder service to help TB patients to remember to take their drugs and to offer them a line of communication to the clinic. The service was rated highly by the participants but was underpowered...

06 September, 2017

Treatment decisions and mortality in HIV-positive presumptive smear-negative TB in the Xpert™ MTB/RIF era: a cohort study

The UNAIDS' HIV this month contains abstracts or summaries of articles and reviews from scientific journals that are carefully filtered from a selection of close to 1000 articles and reviews over a period of one month. The article "Treatment decisions and mortality in HIV-positive presumptive smear-negative...

18 August, 2017

An easy tool to assess ventilation in health facilities as part of air-borne transmission prevention: a cross-sectional survey from Uganda

Brouwer M, Katamba A, Katabira ET, van Leth F. BMC Infect Dis. 2017 May 3;17(1):325. doi: 10.1186/s12879-017-2425-6. https://www.ncbi.nlm.nih.gov/pubmed/28468649 ...

18 July, 2017

Treatment decisions and mortality in HIV-positive presumptive smear-negative TB in the Xpert™ MTB/RIF era: a cohort study

The Xpert™ MTB/RIF (XP) has a higher sensitivity than sputum smear microscopy (70% versus 35%) for TB diagnosis and has been endorsed by the WHO for TB high burden countries to increase case finding among HIV co-infected presumptive TB patients. Its impact on the diagnosis...

18 July, 2017

The Impact of Expanding Access to Early Childhood Education Services in Rural Indonesia

This paper examines the effects of an intervention that expanded access to low-cost, government-sponsored, community-based playgroups in rural Indonesia. Instrumental variables and difference-in-differences models indicate that while the intervention raised enrollment rates and durations of enrollment for everyone, on average, there was little impact on...

18 July, 2017

Delays and loss to follow-up before treatment of drug-resistant tuberculosis following implementation of Xpert MTB/RIF in South Africa

South Africa diagnoses almost 20,000 patients with Rifampicin-resistant tuberculosis each year. A research team comprising Helen Cox (University of Cape Town), AIGHD researchers Anja van’t Hoog and Frank Cobelens, and other colleagues assessed the impact of the Xpert MTB/RIF test (a rapid test for tuberculosis and...

24 February, 2017

Publications

“Data are surprisingly scanty” Recently published systematic review highlights antimicrobial resistance (AMR) knowledge gap in Low- and Middle-income Countries

Starting antiretroviral treatment earlier doesn’t negatively impact adherence and disclosure

NEW PUBLICATION: IP-10 Kinetics in the First Week of Therapy are Strongly Associated with Bacteriological Confirmation of Tuberculosis Diagnosis in HIV-Infected Patients

The impact of the roll-out of rapid molecular diagnostic testing for tuberculosis on empirical treatment in Cape Town, South Africa

Text messaging to decrease tuberculosis treatment attrition in TB-HIV co-infection in Uganda

Treatment decisions and mortality in HIV-positive presumptive smear-negative TB in the Xpert™ MTB/RIF era: a cohort study

An easy tool to assess ventilation in health facilities as part of air-borne transmission prevention: a cross-sectional survey from Uganda

Treatment decisions and mortality in HIV-positive presumptive smear-negative TB in the Xpert™ MTB/RIF era: a cohort study

The Impact of Expanding Access to Early Childhood Education Services in Rural Indonesia

Delays and loss to follow-up before treatment of drug-resistant tuberculosis following implementation of Xpert MTB/RIF in South Africa

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