Sabine Hermans

Projects

Sabine Hermans

  • Assistant Professor, Department of Global Health, Academic Medical Center

Sabine Hermans, MD MSc PhD, is an Assistant Professor at AIGHD and the Department of Global Health, University of Amsterdam. She also works as a clinician at the Department of Tropical Medicine at the AMC.

Sabine trained as an infectious diseases physician (University of Utrecht) and as an epidemiologist (London School of Hygiene and Tropical Medicine, distinction). For her PhD she was based at the Infectious Diseases Institute in Kampala, Uganda, from 2008 to 2012. There she combined set-up and heading of an integrated tuberculosis (TB)/HIV clinic role with her PhD research (jointly supervised by the late Professor Joep Lange and Professor Andy Hoepelman). For her work on integrated TB/HIV care she was awarded the annual International AIDS Society TB-HIV Research Prize in 2011.

A three-year Marie Curie Post-doctoral Fellowship from the European Commission allowed Sabine to join the Desmond Tutu HIV Centre at the University of Cape Town, seconded by AIGHD, from 2013 to 2016. There she worked on epidemiological analyses of a century’s worth of data on TB in Cape Town and helped develop a mathematical model of TB in the city. She also worked as a clinician in Gugulethu.

Her research interests are the epidemiology of HIV and TB (co-)infection, in particular recurrent TB, and optimal health care delivery strategies in sub-Saharan Africa. In this field she has undertaken historical and cost-effectiveness research, and led a prospective study of an mHealth intervention to improve TB treatment completion in Uganda.

In addition to her ongoing work on recurrent TB in South Africa, she is currently the principal investigator of the TB REACH case finding project and leads the clinical and epidemiological research of the Shinyanga HIV Test & Treat project, both in rural Tanzania. She coordinates the weekly AIGHD research meeting and supervises a number of students (BSc, MSc and PhD).

KEY PUBLICATIONS

The impact of the roll-out of rapid molecular diagnostic testing for tuberculosis on empirical treatment in Cape Town, South Africa.
Hermans S, Caldwell J, Kaplan R, Cobelens F, Wood R. Bull
World Health Organ. 2017 Aug 1;95(8):554-563. doi: 10.2471/BLT.16.185314. Epub 2017 Apr 28.

The timing of tuberculosis after isoniazid preventive therapy among gold miners in South Africa: a prospective cohort study.
Hermans SM, Grant AD, Chihota V, Lewis JJ, Vynnycky E, Churchyard GJ, Fielding KL,
BMC MED 2016;14 (1):45

A Century of Tuberculosis Epidemiology in the Northern and Southern Hemisphere: The Differential Impact of Control Interventions.
Hermans S, Horsburgh CR Jr, Wood R,
PLOS ONE 2015;10 (8):e0135179

Temporal trends in TB notification rates during ART scale-up in Cape Town: an ecological analysis.
Hermans S, Boulle A, Caldwell J, Pienaar D, Wood R,
J INT AIDS SOC 2015;18 (1):20240

Integration of HIV and TB Services Results in Improved TB Treatment Outcomes and Earlier Prioritized ART Initiation in a Large Urban HIV Clinic in Uganda.
Hermans SM, Castelnuovo B, Katabira C, Mbidde P, Lange JMA, Hoepelman AIM, Coutinho A, Manabe YC,
JAIDS-J ACQ IMM DEF 2012;60 (2):E29-E35